The single speculative premise
Hard SF's structural principle is often the single speculative premise followed to its logical conclusions: one departure from current science or technology, rigorously extrapolated. The premise should be minimal — the smallest possible change from the actual world that generates the story's central situation — because each additional departure from known science multiplies the research burden and the plausibility challenge. The single-premise approach also produces harder SF: if the only departure from reality is faster-than-light travel, the story's scientific content is the consequences of FTL, not a jumble of incompatible speculations. The discipline of following one premise to its real implications is harder than inventing additional premises to solve problems — and the result is more intellectually satisfying.